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Simulating Dissolution of Intravitreal Triamcinolone Acetonide Suspensions in an Anatomically Accurate Rabbit Eye Model

PURPOSE: A computational fluid dynamics (CFD) study examined the impact of particle size on dissolution rate and residence of intravitreal suspension depots of Triamcinolone Acetonide (TAC). METHODS: A model for the rabbit eye was constructed using insights from high-resolution NMR imaging studies (...

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Hlavní autoři: Missel, Paul J., Horner, Marc, Muralikrishnan, R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896643/
https://ncbi.nlm.nih.gov/pubmed/20467888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0163-1
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