Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif

Spt5 is the only known RNA polymerase-associated factor that is conserved in all three domains of life. We have solved the structure of the Methanococcus jannaschii Spt4/5 complex by X-ray crystallography, and characterized its function and interaction with the archaeal RNAP in a wholly recombinant...

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Bibliografiska uppgifter
Huvudupphovsmän: Hirtreiter, Angela, Damsma, Gerke E., Cheung, Alan C. M., Klose, Daniel, Grohmann, Dina, Vojnic, Erika, Martin, Andrew C. R., Cramer, Patrick, Werner, Finn
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2010
Ämnen:
Nucleic Acid Enzymes
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896526/
https://ncbi.nlm.nih.gov/pubmed/20197319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq135
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