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Spt4/5 stimulates transcription elongation through the RNA polymerase clamp coiled-coil motif
Spt5 is the only known RNA polymerase-associated factor that is conserved in all three domains of life. We have solved the structure of the Methanococcus jannaschii Spt4/5 complex by X-ray crystallography, and characterized its function and interaction with the archaeal RNAP in a wholly recombinant...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896526/ https://ncbi.nlm.nih.gov/pubmed/20197319 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq135 |
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