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Shedding of RANKL by Tumor-Associated MT1-MMP Activates Src-dependent Prostate Cancer Cell Migration
Membrane type-I matrix metalloproteinase (MT1-MMP) plays an essential role in protease-mediated extracellular matrix (ECM)-degradation, but it also functions as a sheddase releasing non-ECM substrates such as Receptor activator of NF-κB ligand (RANKL), an osteoclastogenic factor typically confined t...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896434/ https://ncbi.nlm.nih.gov/pubmed/20551048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-4416 |
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