Beta(1)-Adrenoceptor Polymorphism Predicts Flecainide Action in Patients with Atrial Fibrillation

BACKGROUND: Antiarrhythmic action of flecainide is based on sodium channel blockade. Beta(1)-adrenoceptor (β(1)AR) activation induces sodium channel inhibition, too. The aim of the present study was to evaluate the impact of different β(1)AR genotypes on antiarrhythmic action of flecainide in patien...

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Hauptverfasser: Nia, Amir M., Caglayan, Evren, Gassanov, Natig, Zimmermann, Tom, Aslan, Orhan, Hellmich, Martin, Duru, Firat, Erdmann, Erland, Rosenkranz, Stephan, Er, Fikret
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896398/
https://ncbi.nlm.nih.gov/pubmed/20625396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011421
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