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How antibiotics kill bacteria: from targets to networks

Antibiotic drug-target interactions, and their respective direct effects, are generally well-characterized. In contrast, the bacterial responses to antibiotic drug treatments that contribute to cell death are not as well understood and have proven to be quite complex, involving multiple genetic and...

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Bibliographic Details
Main Authors: Kohanski, Michael A, Dwyer, Daniel J, Collins, James J
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896384/
https://ncbi.nlm.nih.gov/pubmed/20440275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrmicro2333
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