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Deferoxamine treatment for intracerebral hemorrhage in aged rats: therapeutic time window and optimal duration

BACKGROUND AND PURPOSE: Deferoxamine (DFX) reduces brain edema, neurological deficits and brain atrophy after intracerebral hemorrhage (ICH) in aged as well as young rats. Our previous study found that 50 mg/kg is an effective dose in aged rats. In the present study, we explored potential therapeuti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Okauchi, Masanobu, Hua, Ya, Keep, Richard F., Morgenstern, Lewis B., Schallert, Timothy, Xi, Guohua
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896218/
https://ncbi.nlm.nih.gov/pubmed/20044521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.109.569830
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