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Multi-Harmony: detecting functional specificity from sequence alignment

Many protein families contain sub-families with functional specialization, such as binding different ligands or being involved in different protein–protein interactions. A small number of amino acids generally determine functional specificity. The identification of these residues can aid the underst...

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Bibliografiske detaljer
Main Authors: Brandt, Bernd W., Feenstra, K. Anton, Heringa, Jaap
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896201/
https://ncbi.nlm.nih.gov/pubmed/20525785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq415
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