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SeLOX—a locus of recombination site search tool for the detection and directed evolution of site-specific recombination systems

Site-specific recombinases have become a resourceful tool for genome engineering, allowing sophisticated in vivo DNA modifications and rearrangements, including the precise removal of integrated retroviruses from host genomes. In a recent study, a mutant form of Cre recombinase has been used to exci...

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Bibliografske podrobnosti
Main Authors: Surendranath, Vineeth, Chusainow, Janet, Hauber, Joachim, Buchholz, Frank, Habermann, Bianca H.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896191/
https://ncbi.nlm.nih.gov/pubmed/20529878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq523
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