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DrugScore(PPI) webserver: fast and accurate in silico alanine scanning for scoring protein–protein interactions
Protein–protein complexes play key roles in all cellular signal transduction processes. We have developed a fast and accurate computational approach to predict changes in the binding free energy upon alanine mutations in protein–protein interfaces. The approach is based on a knowledge-based scoring...
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| Main Authors: | , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2896140/ https://ncbi.nlm.nih.gov/pubmed/20511591 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq471 |
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