Multi-Scale Modeling of Excitation-Contraction Coupling in the Normal and Failing Heart

Here we describe new computational models of cardiac electromechanics starting from the cellular scale and building to the tissue, organ and system scales. We summarize application to human genetic diseases (LQT1 and LQT3) and to modeling of congestive heart failure.

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Autori principali: Kerckhoffs, Roy C. P., Campbell, Stuart G., Flaim, Sarah N., Howard, Elliot J., Sierra-Aguado, Jazmin, Mulligan, L. J., McCulloch, Andrew D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896048/
https://ncbi.nlm.nih.gov/pubmed/19963818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/IEMBS.2009.5332708
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