Multi-Scale Modeling of Excitation-Contraction Coupling in the Normal and Failing Heart

Here we describe new computational models of cardiac electromechanics starting from the cellular scale and building to the tissue, organ and system scales. We summarize application to human genetic diseases (LQT1 and LQT3) and to modeling of congestive heart failure.

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Detalhes bibliográficos
Main Authors: Kerckhoffs, Roy C. P., Campbell, Stuart G., Flaim, Sarah N., Howard, Elliot J., Sierra-Aguado, Jazmin, Mulligan, L. J., McCulloch, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2896048/
https://ncbi.nlm.nih.gov/pubmed/19963818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/IEMBS.2009.5332708
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