Elevated Oxidative Membrane Damage Associated with Genetic Modifiers of Lyst-Mutant Phenotypes

LYST is a large cytosolic protein that influences the biogenesis of lysosome-related organelles, and mutation of the encoding gene, LYST, can cause Chediak-Higashi syndrome. Recently, Lyst-mutant mice were recognized to also exhibit an iris disease resembling exfoliation syndrome, a common cause of...

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Bibliografiske detaljer
Main Authors: Trantow, Colleen M., Hedberg-Buenz, Adam, Iwashita, Sachiyo, Moore, Steven A., Anderson, Michael G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895641/
https://ncbi.nlm.nih.gov/pubmed/20617205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001008
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