Combined effects of IL-8 and CXCR2 gene polymorphisms on breast cancer susceptibility and aggressiveness

BACKGROUND: Interleukin-8 (IL-8/CXCL-8) is a prototype of the ELR(+)CXC chemokines that play an important role in the promotion and progression of many human cancers including breast cancer. We have recently showed the implication of polymorphism (-251) T/A of IL-8 gene in the susceptibility and pro...

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Detalhes bibliográficos
Main Authors: Snoussi, Kaouther, Mahfoudh, Wijden, Bouaouina, Noureddine, Fekih, Meriem, Khairi, Hedi, Helal, Ahmed N, Chouchane, Lotfi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895614/
https://ncbi.nlm.nih.gov/pubmed/20540789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-283
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