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Presence of two alternative kdr-like mutations, L1014F and L1014S, and a novel mutation, V1010L, in the voltage gated Na(+ )channel of Anopheles culicifacies from Orissa, India

BACKGROUND: Knockdown resistance in insects resulting from mutation(s) in the voltage gated Na(+ )channel (VGSC) is one of the mechanisms of resistance against DDT and pyrethroids. Recently a point mutation leading to Leu-to-Phe substitution in the VGSC at residue 1014, a most common kdr mutation in...

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Detalhes bibliográficos
Main Authors: Singh, Om P, Dykes, Cherry L, Das, Manoj K, Pradhan, Sabyasachi, Bhatt, Rajendra M, Agrawal, Om P, Adak, Tridibes
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895608/
https://ncbi.nlm.nih.gov/pubmed/20509922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-146
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