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RCC1 uses a conformationally diverse loop region to interact with the nucleosome: a model for the RCC1-nucleosome complex
The binding of RCC1 (Regulator of Chromosome Condensation) to chromatin is critical for cellular processes such as mitosis, nucleocytoplasmic transport and nuclear envelope formation because RCC1 recruits the small GTPase Ran to chromatin and sets up a Ran-GTP gradient around the chromosomes. Howeve...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895563/ https://ncbi.nlm.nih.gov/pubmed/20347844 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.03.037 |
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