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Use of Dried Blood Spots in Drug Development: Pharmacokinetic Considerations
Dried blood spots are increasingly being used in drug development. This commentary considers the pharmacokinetic issues that arise and compares these with those attached to plasma, the mainstay matrix. A common implicit use of these matrices is as a surrogate for plasma water, and to this extent, th...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895450/ https://ncbi.nlm.nih.gov/pubmed/20383669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9188-y |
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