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Rainbow Trout (Oncorhynchus mykiss) and Ultra-Low Dose Cancer Studies
Cancer risk assessment utilizing rodents requires extrapolation across five orders of magnitude to estimate the Virtually Safe Dose (VSD). Regulatory agencies rely upon the Linear Extrapolated Dose (LED) except when sufficient information on mechanism of action justifies alternative models. Rainbow...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2895404/ https://ncbi.nlm.nih.gov/pubmed/19135172 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpc.2008.12.002 |
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