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Calcium Domains around Single and Clustered IP(3) Receptors and Their Modulation by Buffers

We study Ca(2+) release through single and clustered IP(3) receptor channels on the ER membrane under presence of buffer proteins. Our computational scheme couples reaction-diffusion equations and a Markovian channel model and allows our investigating the effects of buffer proteins on local calcium...

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Autors principals: Rüdiger, S., Nagaiah, Ch., Warnecke, G., Shuai, J.W.
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895387/
https://ncbi.nlm.nih.gov/pubmed/20655827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.02.059
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