Actomyosin Tension Exerted on the Nucleus through Nesprin-1 Connections Influences Endothelial Cell Adhesion, Migration, and Cyclic Strain-Induced Reorientation

Endothelial cell polarization and directional migration is required for angiogenesis. Polarization and motility requires not only local cytoskeletal remodeling but also the motion of intracellular organelles such as the nucleus. However, the physiological significance of nuclear positioning in the e...

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Bibliographic Details
Main Authors: Chancellor, T.J., Lee, Jiyeon, Thodeti, Charles K., Lele, Tanmay
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Cellular Biophysics and Electrophysiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895377/
https://ncbi.nlm.nih.gov/pubmed/20655839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.04.011
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