Mitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressive

Condensation and segregation of mitotic chromosomes is a critical process for cellular propagation, and, in mammals, mitotic errors can contribute to the pathogenesis of cancer. In this report, we demonstrate that the retinoblastoma protein (pRB), a well-known regulator of progression through the G1...

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Autori principali: Coschi, Courtney H., Martens, Alison L., Ritchie, Kieran, Francis, Sarah M., Chakrabarti, Subrata, Berube, Nathalie G., Dick, Frederick A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2010
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895195/
https://ncbi.nlm.nih.gov/pubmed/20551166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1917610
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