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Engineered bacterial communication prevents Vibrio cholerae virulence in an infant mouse model

To investigate the possibility of using commensal bacteria as signal mediators for inhibiting the disease cholera, we stably transformed Escherichia coli Nissle 1917 (Nissle) to express the autoinducer molecule cholera autoinducer 1 (CAI-1) (shown previously to prevent virulence when present with an...

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Detalhes bibliográficos
Main Authors: Duan, Faping, March, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895089/
https://ncbi.nlm.nih.gov/pubmed/20534565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001294107
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