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IRAK1BP1 inhibits inflammation by promoting nuclear translocation of NF-κB p50

An orchestrated balance of pro- and antiinflammatory cytokine release is critical for an innate immune response sufficient for pathogen defense without excessive detriment to host tissues. By using an unbiased forward genetic approach, we previously reported that IL-1R–associated kinase 1 binding pr...

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Detalhes bibliográficos
Main Authors: Conner, James R., Smirnova, Irina I., Moseman, Annie Park, Poltorak, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895073/
https://ncbi.nlm.nih.gov/pubmed/20534545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1006894107
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