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Visualizing high error levels during gene expression in living bacterial cells

To monitor inaccuracy in gene expression in living cells, we designed an experimental system in the bacterium Bacillus subtilis whereby spontaneous errors can be visualized and quantified at a single-cell level. Our strategy was to introduce mutations into a chromosomally encoded gfp allele, such th...

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Detalles Bibliográficos
Main Authors: Meyerovich, Mor, Mamou, Gideon, Ben-Yehuda, Sigal
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895060/
https://ncbi.nlm.nih.gov/pubmed/20534550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912989107
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