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NAD(P)H Quinone Oxidoreductase Protects TAp63γ from Proteasomal Degradation and Regulates TAp63γ-Dependent Growth Arrest
BACKGROUND: p63 is a member of the p53 transcription factor family. p63 is expressed from two promoters resulting in proteins with opposite functions: the transcriptionally active TAp63 and the dominant-negative ΔNp63. Similar to p53, the TAp63 isoforms induce cell cycle arrest and apoptosis. The ΔN...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894944/ https://ncbi.nlm.nih.gov/pubmed/20613985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011401 |
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