The ERα coactivator, HER4/4ICD, regulates progesterone receptor expression in normal and malignant breast epithelium

The HER4 intracellular domain (4ICD) is a potent estrogen receptor (ERα) coactivator with activities in breast cancer and the developing mammary gland that appear to overlap with progesterone receptor (PgR). In fact, 4ICD has recently emerged as an important regulator and predictor of tamoxifen resp...

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Bibliographic Details
Main Authors: Rokicki, Jerzy, Das, Partha M, Giltnane, Jennifer M, Wansbury, Olivia, Rimm, David L, Howard, Beatrice A, Jones, Frank E
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894764/
https://ncbi.nlm.nih.gov/pubmed/20550710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-150
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