Cyclic nucleotides and mitogen-activated protein kinases: regulation of simvastatin in platelet activation

BACKGROUND: 3-Hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have been widely used to reduce cardiovascular risk. These statins (i.e., simvastatin) may exert other effects besides from their cholesterol-lowering actions, including inhibition of platelet activation. Pla...

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Detalhes bibliográficos
Main Authors: Lee, Ye-Ming, Chen, Wei-Fan, Chou, Duen-Suey, Jayakumar, Thanasekaran, Hou, Ssu-Yu, Lee, Jie-Jen, Hsiao, George, Sheu, Joen-Rong
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894762/
https://ncbi.nlm.nih.gov/pubmed/20525309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-17-45
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