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Cyclopropanation of nitroso Diels–Alder cycloadducts and application to the synthesis of a 2’,3’-methano carbocyclic nucleoside

Treatment of nitroso Diels–Alder cycloadducts 1 with diazomethane in the presence of palladium acetate gives synthetically useful exo-6-oxa-7-azatricyclo[3.2.1.02,4]octane derivatives 7 in good to excellent yield. Using this methodology, a conformationally restricted 2’,3’-methano carbocyclic nucleo...

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Detalhes bibliográficos
Main Authors: Ji, Cheng, Miller, Marvin J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894734/
https://ncbi.nlm.nih.gov/pubmed/20607121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2010.05.062
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