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In vivo tracking of ‘color-coded’ effector, natural and induced regulatory T cells in the allograft response

Here we present methods to longitudinally track islet allograft—infiltrating T cells in live mice by endoscopic confocal microscopy and to analyze circulating T cells by in vivo flow cytometry. We developed a new reporter mouse whose T cell subsets express distinct, ‘color-coded’ proteins enabling i...

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Bibliografiske detaljer
Main Authors: Fan, Zhigang, Spencer, Joel A, Lu, Yan, Pitsillides, Costas M, Singh, Gurbakhshish, Kim, Pilhan, Yun, Seok H, Toxavidis, Vasilis, Strom, Terry B, Lin, Charles P, Koulmanda, Maria
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894571/
https://ncbi.nlm.nih.gov/pubmed/20495571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2155
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