Vinculin potentiates E-cadherin mechanosensing and is recruited to actin-anchored sites within adherens junctions in a myosin II–dependent manner

Cell surface receptors integrate chemical and mechanical cues to regulate a wide range of biological processes. Integrin complexes are the mechanotransducers between the extracellular matrix and the actomyosin cytoskeleton. By analogy, cadherin complexes may function as mechanosensors at cell–cell j...

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Hlavní autoři: le Duc, Quint, Shi, Quanming, Blonk, Iris, Sonnenberg, Arnoud, Wang, Ning, Leckband, Deborah, de Rooij, Johan
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2010
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894457/
https://ncbi.nlm.nih.gov/pubmed/20584916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001149
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