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Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability
Mitotic spindles play essential roles in chromosome congression and segregation during mitosis. Aurora A regulates spindle assembly in part via phosphorylating human TACC3 on S558, which triggers TACC3 relocalization to mitotic spindles and stabilizes microtubules (MTs). In this study, we identified...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894451/ https://ncbi.nlm.nih.gov/pubmed/20566684 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200911120 |
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