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The nucleoporin Nup188 controls passage of membrane proteins across the nuclear pore complex

All transport across the nuclear envelope (NE) is mediated by nuclear pore complexes (NPCs). Despite their enormous size, ∼60 MD in vertebrates, they are comprised of only ∼30 distinct proteins (nucleoporins or Nups), many of which form subcomplexes that act as building blocks for NPC assembly. One...

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Autors principals: Theerthagiri, Gandhi, Eisenhardt, Nathalie, Schwarz, Heinz, Antonin, Wolfram
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894445/
https://ncbi.nlm.nih.gov/pubmed/20566687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200912045
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