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Classic hippocampal sclerosis and hippocampal-onset epilepsy produced by a single “cryptic” episode of focal hippocampal excitation in awake rats

In refractory temporal lobe epilepsy, seizures often arise from a shrunken hippocampus exhibiting a pattern of selective neuron loss called “classic hippocampal sclerosis.” No single experimental injury has reproduced this specific pathology, suggesting that hippocampal atrophy might be a progressiv...

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Detalhes bibliográficos
Main Authors: Norwood, Braxton A., Bumanglag, Argyle V., Osculati, Francesco, Sbarbati, Andrea, Marzola, Pasquina, Nicolato, Elena, Fabene, Paolo F., Sloviter, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894278/
https://ncbi.nlm.nih.gov/pubmed/20575073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cne.22406
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