Methylation of the Tumor Suppressor Protein, BRCA1, Influences Its Transcriptional Cofactor Function

BACKGROUND: Approximately half of hereditary breast cancers have mutations in either BRCA1 or BRCA2. BRCA1 is a multifaceted tumor suppressor protein that has implications in processes such as cell cycle, transcription, DNA damage response and chromatin remodeling. This multifunctional nature of BRC...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Guendel, Irene, Carpio, Lawrence, Pedati, Caitlin, Schwartz, Arnold, Teal, Christine, Kashanchi, Fatah, Kehn-Hall, Kylene
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2010
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894074/
https://ncbi.nlm.nih.gov/pubmed/20614009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011379
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