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Dynamin I phosphorylation by GSK3 controls activity-dependent bulk endocytosis of synaptic vesicles
Glycogen synthase kinase-3 (GSK3) is a critical enzyme in neuronal physiology, however any specific role in presynaptic function is not yet known. We show that GSK3 phosphorylates a key residue on the large GTPase dynamin I (Ser-774) both in vitro and in primary rat neuronal cultures. This is depend...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894011/ https://ncbi.nlm.nih.gov/pubmed/20526333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.2571 |
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