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Combined effect of regulatory polymorphisms on transcription of UGT1A1 as a cause of Gilbert syndrome
BACKGROUND: Gilbert syndrome is caused by defects in bilirubin UDP-glucuronosyltransferase (UGT1A1). The most common variation believed to be involved is A(TA)7TAA. Although several polymorphisms have been found to link with A(TA)7TAA, the combined effect of regulatory polymorphisms in the developme...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2894006/ https://ncbi.nlm.nih.gov/pubmed/20529348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-10-57 |
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