Human Mucosal Associated Invariant T Cells Detect Bacterially Infected Cells

Control of infection with Mycobacterium tuberculosis (Mtb) requires Th1-type immunity, of which CD8(+) T cells play a unique role. High frequency Mtb-reactive CD8(+) T cells are present in both Mtb-infected and uninfected humans. We show by limiting dilution analysis that nonclassically restricted C...

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Bibliographic Details
Main Authors: Gold, Marielle C., Cerri, Stefania, Smyk-Pearson, Susan, Cansler, Meghan E., Vogt, Todd M., Delepine, Jacob, Winata, Ervina, Swarbrick, Gwendolyn M., Chua, Wei-Jen, Yu, Yik Y. L., Lantz, Olivier, Cook, Matthew S., Null, Megan D., Jacoby, David B., Harriff, Melanie J., Lewinsohn, Deborah A., Hansen, Ted H., Lewinsohn, David M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893946/
https://ncbi.nlm.nih.gov/pubmed/20613858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000407
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