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New Method to Prepare Mitomycin C Loaded PLA-Nanoparticles with High Drug Entrapment Efficiency

The classical utilized double emulsion solvent diffusion technique for encapsulating water soluble Mitomycin C (MMC) in PLA nanoparticles suffers from low encapsulation efficiency because of the drug rapid partitioning to the external aqueous phase. In this paper, MMC loaded PLA nanoparticles were p...

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Detalhes bibliográficos
Main Authors: Hou, Zhenqing, Wei, Heng, Wang, Qian, Sun, Qian, Zhou, Chunxiao, Zhan, Chuanming, Tang, Xiaolong, Zhang, Qiqing
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893904/
https://ncbi.nlm.nih.gov/pubmed/20596446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11671-009-9312-z
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