Myeloid CD34(+)CD13(+) Precursor Cells Transdifferentiate into Chondrocyte-Like Cells in Atherosclerotic Intimal Calcification

Chondrogenic differentiation is pivotal in the active regulation of artery calcification. We investigated the cellular origin of chondrocyte-like cells in atherosclerotic intimal calcification of C57BL/6 LDLr(−/−) mice using bone marrow transplantation to trace ROSA26-LacZ-labeled cells. Immunohisto...

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Hoofdauteurs: Doehring, Lars Christian, Heeger, Christian, Aherrahrou, Zouhair, Kaczmarek, Piotr Maciel, Erdmann, Jeanette, Schunkert, Heribert, Ehlers, Eva-Maria
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893689/
https://ncbi.nlm.nih.gov/pubmed/20489139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090758
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