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Selective Cell Death of Hyperploid Neurons in Alzheimer’s Disease

Aneuploidy, an abnormal number of copies of a genomic region, might be a significant source for neuronal complexity, intercellular diversity, and evolution. Genomic instability associated with aneuploidy, however, can also lead to developmental abnormalities and decreased cellular fitness. Here we s...

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Detalhes bibliográficos
Main Authors: Arendt, Thomas, Brückner, Martina K., Mosch, Birgit, Lösche, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893646/
https://ncbi.nlm.nih.gov/pubmed/20472889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090955
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