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Effects of Buffer Loading for Electrospray Ionization Mass Spectrometry of a Noncovalent Protein Complex that Requires High Concentrations of Essential Salts

Electrospray ionization (ESI) mass spectrometry (MS) is a powerful method for analyzing the active forms of macromolecular complexes of biomolecules. However, these solutions often contain high concentrations of salts and/or detergents that adversely effect ESI performance by making ion formation le...

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Bibliografiske detaljer
Main Authors: Sterling, Harry J., Batchelor, Joseph D., Wemmer, David E., Williams, Evan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893594/
https://ncbi.nlm.nih.gov/pubmed/20226685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2010.02.003
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