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JAK-STAT is restrained by Notch to control cell proliferation of the Drosophila intestinal stem cells
The Drosophila midgut epithelium undergoes continuous regeneration by multipotent intestinal stem cells (ISCs). Notch signaling has dual functions to control the ISCs behavior: it slows down the ISCs proliferation and drives the activated ISCs into differentiation pathways in a dose-dependent manner...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2893559/ https://ncbi.nlm.nih.gov/pubmed/20082318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22482 |
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