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Role played by Th2 type cytokines in IgE mediated allergy and asthma

OBJECTIVE: Recent evidence suggest that allergen type 2 helper T cells (Th2) play a triggering role in the activation/recruitment of IgE antibody producing B cells, mast cells and eosinophils. Reduced microbial exposure in early life is responsible for a shift of Th1/Th2 balance in the immune system...

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Main Authors: Deo, Sudha S., Mistry, Kejal J., Kakade, Amol M., Niphadkar, Pramod V.
Format: Artigo
Sprog:Inglês
Udgivet: Medknow Publications 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893428/
https://ncbi.nlm.nih.gov/pubmed/20616938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0970-2113.63609
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