Comparison of germ line minisatellite mutation detection at the CEB1 locus by Southern blotting and PCR amplification

Identification of de novo minisatellite mutations in the offspring of parents exposed to mutagenic agents offers a potentially sensitive measure of germ line genetic events induced by ionizing radiation and genotoxic chemicals. Germ line minisatellite mutations (GMM) are usually detected by hybridiz...

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Main Authors: Taylor, Malcolm, Cieslak, Marcin, Rees, Gwen S., Oojageer, Anthony, Leith, Cheryl, Bristow, Claire, Tawn, E. Janet, Winther, Jeanette F., Boice, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893306/
https://ncbi.nlm.nih.gov/pubmed/20228094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/mutage/geq011
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