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Object/context-specific memory deficits associated with loss of hippocampal granule cells after adrenalectomy in rats

Chronic adrenalectomy (ADX) causes a gradual and selective loss of granule cells in the dentate gyrus (DG) of the rat. Here, we administered replacement corticosterone to rats beginning 10 wk after ADX. We then tested them in three discrimination tasks based on object novelty, location, or object/co...

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Autori principali: Spanswick, Simon C., Sutherland, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893217/
https://ncbi.nlm.nih.gov/pubmed/20410060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.1746710
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