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Tick saliva is a potent inhibitor of endothelial cell proliferation and angiogenesis

We report for the first time that saliva of the hard tick and Lyme disease vector, Ixodes scapularis, is a potent inhibitor of angiogenesis. Saliva (≤ 1:500 dilutions) or salivary gland (0.1–0.5 pairs/assay) dose-dependently inhibits microvascular endothelial cell (MVEC) proliferation. Inhibition wa...

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Bibliografiske detaljer
Main Authors: Francischetti, Ivo M. B., Mather, Thomas N., Ribeiro, José M. C.
Format: Artigo
Sprog:Inglês
Udgivet: 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893037/
https://ncbi.nlm.nih.gov/pubmed/16113800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1267/THRO05010167
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