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IGF-1-induced phosphorylation and altered distribution of TSC1/TSC2 in C2C12 myotubes

Insulin like growth factor-1 (IGF-1) is established as an anabolic factor that can induce skeletal muscle growth through activating the phosphoinositide 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway. While this signaling pathway has been heavily studied, the molecular mechanisms l...

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Detalhes bibliográficos
Main Authors: Miyazaki, Mitsunori, McCarthy, John J, Esser, Karyn A
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892984/
https://ncbi.nlm.nih.gov/pubmed/20412061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07635.x
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