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Immunofluorescence-based assay to identify modulators of the number of plasma membrane KCa3.1 channels

BACKGROUND: Intermediate conductance Ca(2+)-dependent K(+) channels (KCa3.1) have been proposed as therapeutic targets for numerous diseases. We recently characterized the endocytic fate of these channels; leading to the possibility that this can be pharmacologically manipulated, thereby altering th...

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Bibliographic Details
Main Authors: Balut, Corina M, Gao, Yajuan, Luke, Cliff, Devor, Daniel C
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892982/
https://ncbi.nlm.nih.gov/pubmed/20596245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.10.182
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