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Somatic FAS mutations are common in patients with genetically undefined autoimmune lymphoproliferative syndrome
Autoimmune lymphoproliferative syndrome (ALPS) is characterized by childhood onset of lymphadenopathy, hepatosplenomegaly, autoimmune cytopenias, elevated numbers of double-negative T (DNT) cells, and increased risk of lymphoma. Most cases of ALPS are associated with germline mutations of the FAS ge...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2892951/ https://ncbi.nlm.nih.gov/pubmed/20360470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-263145 |
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