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Comparison of twice-daily vs once-daily deferasirox dosing in a gerbil model of iron cardiomyopathy

OBJECTIVE: Despite the availability of deferoxamine chelation therapy for more than 20 years, iron cardiomyopathy remains the leading cause of death in thalassemia major patients. Effective chelation of cardiac iron is difficult; cardiac iron stores respond more slowly to chelation therapy and requi...

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Detalhes bibliográficos
Main Authors: Otto-Duessel, Maya, Aguilar, Michelle, Nick, Hanspeter, Moats, Rex, Wood, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892931/
https://ncbi.nlm.nih.gov/pubmed/17588475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2007.04.001
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