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Systematic Reduction of Cohesin Differentially Affects Chromosome Segregation, Condensation, and DNA Repair

Cohesin’s complex distribution on chromosomes and its implication in numerous cellular processes makes it an excellent paradigm for studying the relationship between the in vivo concentration of a protein and its in vivo function. Here, we report a method to generate systematic quantized reductions...

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Autors principals: Heidinger-Pauli, Jill M., Mert, Ozlem, Davenport, Carol, Guacci, Vincent, Koshland, Douglas
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892909/
https://ncbi.nlm.nih.gov/pubmed/20451387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2010.04.018
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